Dense growths of Bell's honeysuckle can supress native plant and timber regeneration and create monocultures. Infestations can substantial reduce ecosystem richness and density of tree seedlings. This species can alter a habitat's microclimate by creating dense shade, and depleting soil soil and nutrients. It can reduce growth of native plants by releasing allelopathic chemicals. It can be especially harmful to spring ephemerals, because of its early leafing.